Korea Process Technology

제품명 : KAH-BASIC Most cost-effective universal homogenizer

Application Category

• Biology: cell disruption, enzyme engineering, protein drugs

• Pharmacy: liposomes, fat emulsion, nanoparticles, etc.

• Food, cosmetics, Fine Chemicals,etc.

Techniques

Project	Basic 1	Basic 2
Maxumum working pressure	1500bar/150Mpa/22500ps	1000bar/100Mpa/15000psi
Maximum design pressure	1800bar/180Mpa/27000ps	1200bar/120Moa/18000osi
Processing capacity	10L/H	20L/H
The minimum processing volume	25 ml	25 ml
Material consumption	0ml(No residue)	0ml(No residue)
Motor Power	1.5kw/380V/50Hz	1.5kw/380V/50Hz
Dimensions	W440H410L800	W440H410L800
Weight	110kg	110kg

High-pressure Homogenizer Applications

Application Introduction

Biological articles

Cell disruption

Applicable type of bacteria

E. coli, Yeast, Algal cells, Animal cells, Insect cells

Crushing principle

Plunger movement carries sample to a valve assembly which size can be adjusted. Samples received ultrahigh pressures squeeze, through the specific slit width. Instantaneous release of pressure to high-speed crash in the homogenizing valve. Bring about cavitation, impace effect shearing effect:So as to achieve a homogenous, emulsification, dispersion effect

Techniques

• > 99% fragmentation rate

• Built-in temperature control device:direct cooling of the working part,the temperature can be controlled at below 10 °C, the samples had no time in with high temperature residen

• PLC control: optional PLC control systems, production data monitoring, collection and output

• Modular design: The device fully modular design, can achieve SIP / CIP

• Resuspended bacterial system can be configured

• Compliance with GMP / FDA requirements

Pharmaceutical, fine chemical

Applicable type of bacteria

Pharmaceutical : Emulsifier, Suspension and other types of drugs

Fine chemical : Nanospheres, Conductive material

Techniques

Uniformity control	Particle size control	Temperature control	Data record
( Two-level homogeneous ) • The samples could be homogenized and dispersed in first stag • The sample would be further dispersed evenly in the second stage • Agglomerated particles would be dispersed and PDI is less than 0.1	• Fat emulsion particle size <0.2um • Liposome particle size<0. 1um • Fine Chemical System Stability	Internal and external temperature control at the same time, can be adjusted within the range of 5-100 °C	Monitor the whole process, in line with GMP / FDA standards

Uniformity control

Particle size control

Temperature control

Data record

( Two-level homogeneous )

• The samples could be homogenized and dispersed in first stag

• The sample would be further dispersed evenly in the second stage

• Agglomerated particles would be dispersed and PDI is less than 0.1

• Fat emulsion particle size <0.2um

• Liposome particle size<0. 1um

• Fine Chemical System Stability

Internal and external temperature control at the same time, can be adjusted within the range of 5-100 °C

Monitor the whole process, in line with GMP / FDA standards

Pharmacy System